This calculator program utilizes the Dipeptide Instability Weight Values (DIWV) published by Guruprasad et al. Enter single-letter amino acid sequence to calculate Instability Index value

Calculate        Clear

Guruprasad, K., B. V. Reddy, et al. (1990). "Correlation between stability of a protein and its dipeptide composition: a novel approach for predicting in vivo stability of a protein from its primary sequence." Protein Eng 4(2): 155-61.