BIO 3520
McGilliard
 

RENAL PHYSIOLOGY



Reading Assignment:

 

     Widmaier, pp. 525-552, 563, 567-572.
 

 

Objectives:

 

     After reviewing your lecture notes and reading assignment, you should be able to:

 

     1.  Describe the primary function of the urinary system and list four general functions
          of the kidneys.

 

          Lecture -- 11/10
          Text -- pg. 526
          Table -- 14-1
          Notes

 

     2.  Draw a diagram of a nephron and identify the following parts:
          a.  Glomerulus.
          b.  Bowman's capsule.
          c.  Proximal tubule.
          d.  Loop of Henle.
          e.  Distal tubule.
          f.  Collecting duct.

 

          Lecture -- 11/10
          Text -- pp. 526-530
          Figures -- 14-2a, 14-2b, 14-4
          Film:  Work of the Kidneys
          Anatomy of the Kidney (quiz yourself)

 

     3.  Identify the functions of each of the above parts, including their roles in the
          filtration, reabsorption, or secretion of sodium, chloride, and water.

          Lecture -- 11/10, 11/13
          Text -- pp. 530-537, 541-547
          Figure -- 14-6
          Film:  Work of the Kidneys
          Notes

 

     4.  Describe the renal circulation, beginning with the renal artery and ending with the
          renal vein.

 

          Lecture -- 11/10
          Text -- pp. 527-530
          Figure -- 14-2a
          Renal Circulation
          Nephron and Renal Circulation
          Film:  Work of the Kidneys

 

     5.  Discuss the process of glomerular filtration and describe how the glomerular
          filtration rate is measured.

 

          Lecture -- 11/12
          Text -- pp. 532-534
          Figures -- 14-3, 14-8
          Glomerulus
          Glomerular Filtration
          Film:  Work of the Kidneys
          Notes

 

     6.  Define clearance and calculate the renal clearance of a substance.

 

          Lecture -- 11/12
          Text -- pp. 537-538
          Notes

 

     7.  Define tubular secretion, describe its mechanism, and give three examples of
          substances that are secreted.

 

          Lecture -- 11/12
          Text -- pp. 530-531, 536
          Figures -- 14-6, 14-7
          Tubular Reabsorption and Secretion
          Film:  Work of the Kidneys
          Notes

 

     8.  Describe, in general terms, the role of the kidneys in acid-base balance.

 

          Lecture -- 11/12, 11/15
          Text -- pp. 563, 568
          Table -- 14-9
          Notes

 

     9.  Define tubular reabsorption, describe its mechanism, and give three examples of
          substances that are reabsorbed.

 

          Lecture -- 11/15
          Text -- pp. 530-532, 534-537, 541-542
          Figures -- 14-6, 14-7, 14-13
          Table -- 14-2

          Tubular Reabsorption and Secretion
          Film:  Work of the Kidneys
          Notes

 

   10.  Describe the mechanism by which most diuretics increase urination and help to
          reduce blood pressure.

 

          Lecture -- 11/15
          Text -- pp. 569-570
          Notes

 

   11.  Describe the regulation of sodium excretion by the renin-angiotensin-aldosterone
          system.

 

          Lecture -- 11/15, 11/17
          Text -- pp. 548-550
          Figures -- 14-5, 14-19, 14-20

 

   12.  Describe the role of antidiuretic hormone (vasopressin) in the regulation of water
          balance.

 

          Lecture -- 11/17, 11/19
          Text -- pp. 543-546, 550-552
          Figures -- 14-15, 14-23
          Osmotic Gradients in the Kidney
          Film:  Work of the Kidneys

 

   13.  Discuss the effects of hydration, dehydration, and salt intake on urine volume and
          specific gravity.

 

          Lecture/Lab -- 11/14-11/16
          Text -- pp. 551-552
          Figure -- 14-23
          Urinalysis:  Worksheet

 

   14.  Discuss the adaptation of desert-dwelling mammals to a dry environment.

 

          Lecture -- 11/17

 

   15.  Describe the path of urine flow from the kidney to the urethra.

 

          Lecture -- 11/08
          Text -- pg. 526
          Figure -- 14-1
          Anatomy of the Urinary System

 

   16.  Describe the micturition reflex.

 

          Lecture -- 11/17
          Text -- pp. 538-539
          Figure -- 14-12

          Micturition Reflex

 

   17.  Describe the physiological basis of each of the following disorders:

          a.  Urinary incontinence.
          b.  Kidney stones.
          c.  Renal failure.

 

          Lecture -- 11/17
          Text -- pp. 539, 570-571
          Kidney Stones
          Film:  Work of the Kidneys
          Notes

 

   18.  Describe the processes of dialysis and kidney transplantation.

 

          Lecture --
          Text -- pp. 571-572
          Figure -- 14-36
          Film:  Work of the Kidneys

 

   19.  Discuss how disorders of the urinary system or metabolism can be identified by

          chemical analysis of a urine sample.
 

          Lab -- 11/18, 11/19

          Text -- pp. 536, 570

          Urinalysis:  Worksheet

 

 

Review Questions:

 

     Pg. 540, #1, 3, 4, 5, 7, 8.
     Pg. 557, #6, 11, 12.
     Pg. 569, #8.
 

Test Questions:

 

     Pp. 572-573, #1, 2, 5.

 

Thought Questions:

 

     Pg. 573, #2, 3, 8.
 
 

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Updated 11/09/06