RENAL PHYSIOLOGY
Reading Assignment:
Widmaier, pp. 525-552, 563, 567-572.
Objectives:
After reviewing your lecture notes and reading assignment, you should be able to:
1. Describe the primary function of the
urinary system and list four general functions
of the kidneys.
Lecture -- 11/10
Text
-- pg. 526
Table --
14-1
Notes
2. Draw a diagram of a nephron and identify
the following parts:
a. Glomerulus.
b. Bowman's
capsule.
c. Proximal
tubule.
d. Loop of Henle.
e. Distal tubule.
f. Collecting
duct.
Lecture -- 11/10
Text
-- pp. 526-530
Figures --
14-2a,
14-2b,
14-4
Film:
Work of the Kidneys
Anatomy
of the Kidney (quiz yourself)
3. Identify the functions of each of the
above parts, including their roles in the
filtration, reabsorption, or secretion of sodium, chloride, and water.
Lecture -- 11/10,
11/13
Text -- pp.
530-537, 541-547
Figure --
14-6
Film:
Work of the Kidneys
Notes
4. Describe the renal circulation, beginning
with the renal artery and ending with the
renal vein.
Lecture -- 11/10
Text -- pp. 527-530
Figure --
14-2a
Renal
Circulation
Nephron
and Renal Circulation
Film:
Work of the Kidneys
5. Discuss the process of glomerular filtration
and describe how the glomerular
filtration rate is measured.
Lecture -- 11/12
Text -- pp. 532-534
Figures --
14-3,
14-8
Glomerulus
Glomerular
Filtration
Film:
Work of the Kidneys
Notes
6. Define clearance and calculate the renal clearance of a substance.
Lecture -- 11/12
Text -- pp. 537-538
Notes
7. Define tubular secretion, describe its mechanism,
and give three examples of
substances
that are secreted.
Lecture -- 11/12
Text -- pp.
530-531, 536
Figures --
14-6,
14-7
Tubular
Reabsorption and Secretion
Film:
Work of the Kidneys
Notes
8. Describe, in general terms, the role of the kidneys in acid-base balance.
Lecture -- 11/12,
11/15
Text -- pp.
563, 568
Table --
14-9
Notes
9. Define tubular reabsorption, describe its mechanism,
and give three examples of
substances
that are reabsorbed.
Lecture -- 11/15
Text -- pp.
530-532, 534-537, 541-542
Figures --
14-6,
14-7,
14-13
Table -- 14-2
Tubular
Reabsorption and Secretion
Film:
Work of the Kidneys
Notes
10. Describe the mechanism by which most diuretics increase
urination and help to
reduce
blood pressure.
Lecture -- 11/15
Text -- pp. 569-570
Notes
11. Describe the regulation of sodium excretion by the renin-angiotensin-aldosterone
system.
Lecture -- 11/15,
11/17
Text -- pp. 548-550
Figures --
14-5,
14-19,
14-20
12. Describe the role of antidiuretic hormone (vasopressin)
in the regulation of water
balance.
Lecture -- 11/17,
11/19
Text -- pp.
543-546, 550-552
Figures --
14-15,
14-23
Osmotic
Gradients in the Kidney
Film:
Work of the Kidneys
13. Discuss the effects of hydration, dehydration, and salt
intake on urine volume and
specific gravity.
Lecture/Lab --
11/14-11/16
Text -- pp. 551-552
Figure --
14-23
Urinalysis:
Worksheet
14. Discuss the adaptation of desert-dwelling mammals to a dry environment.
Lecture -- 11/17
15. Describe the path of urine flow from the kidney to the urethra.
Lecture -- 11/08
Text -- pg. 526
Figure --
14-1
Anatomy
of the Urinary System
16. Describe the micturition reflex.
Lecture -- 11/17
Text -- pp. 538-539
Figure --
14-12
17. Describe the physiological basis of each of the following disorders:
a. Urinary incontinence.
b. Kidney
stones.
c. Renal
failure.
Lecture -- 11/17
Text -- pp.
539, 570-571
Kidney
Stones
Film:
Work of the Kidneys
Notes
18. Describe the processes of dialysis and kidney transplantation.
Lecture --
Text -- pp. 571-572
Figure --
14-36
Film: Work of the Kidneys
19. Discuss how disorders of the urinary system or metabolism can be identified by
chemical
analysis of a urine sample.
Lab -- 11/18, 11/19
Text -- pp. 536, 570
Review Questions:
Pg. 540, #1, 3, 4, 5, 7,
8.
Pg. 557, #6, 11, 12.
Pg. 569, #8.
Test Questions:
Pp. 572-573, #1, 2, 5.
Thought Questions:
Pg. 573, #2, 3, 8.
Updated 11/09/06