TABLE OF CONTENTS
Grade Determination 2
Introduction 4
Skeletal System 7
Skull 14
Arthology 16
Skeletal Muscle System 18
Hematology 26
Respiratory System 29
Cardiovascular System 33
Schematic Summary of Systemic Arteries 38
Schematic Summary of Systemic Veins 39
Lymphatic System 40
Lymphoid Organs 41
Digestive System 42
Urinary System 51
Neurology 55
Brain 56
Spinal Cord 59
Spinal Nerves 61
Cranial Nerves 64
Autonomic Nervous System 66
Sensory Structures- Taste & Smell 69
Special Senses- Ear 70
Special Senses- Eye 72
Endocrine System 75
Integumentary System 79
Reproductive System 81
Pregnancy -> Birth 85
Test Bank 87
Mammalian Anatomy- Zoology 2000
One's performance in Zoo 2000 will be determined by your demonstrated knowledge of core material (human systems and cat dissection), which will determine if one passes or fails to pass, and the calculation of final (letter) grades.
The Minimum Criteria for Passing.
The following mechanisms will be used to test one's knowledge of the course material. They will determine if you pass or fail. The following is an EXAMPLE set of criteria:
Midterms (2) =~ 100 pts each, (total =_~ 200 pts).
Exams 1- (3) =~ 50 pts each, (total =_~ 150 pts).
Practicals(3) =~ 50 pts each, (total =_~ 150 pts).
Final Exam =~ 200 pts.
Total Points = 700 (approximate).
You ARE expected to achieve a minimum rank of 60%.
How Final Grades will be Determined.
Final Letter Grades will be based on one's percentile score and assigned as follows:
89.9 to 100% = A
79.9 to 89.8 = B
69.1 to 79.8 = C
less than 69 = D.
less than 59.9 = F.
Therefore, if 700 = greatest individual total number of points, then the following would apply:
629 to 700 = A
553 to 628 = B
483 to 552 = C
420 to 482 = D
less than 420 = F.
PLEASE NOTE:
IN ORDER TO PASS THIS COURSE,
one must obtain an
ABSOLUTE MINIMUM SCORE
of 60.0%.
IN ADDITION:
1. THIS ENTIRE COURSE IS CUMMULATIVE. THE FINAL WILL ENCOMPASS
or COVER THE ENTIRE SEMESTER.
2. I shall do all I can to make the material understandable. Your questions are strongly encouraged.
Remember, THERE IS NO SUCH THING A STUPID QUESTION- ONLY STUPID
ANSWERS.
3. I am available to assist your learning in any mutually agreeable fashion.
4. I will notify you if your performance is not adequate.
HOWEVER:
5. BE ADVISED THAT I will not be responsible to make you participate in this course or to make you learn this material. You, as young adults, are responsible for your own motivation. To paraphrase, "I can lead you to water, but I cannot make you drink."
6. Bear in mind that this study guide is NOT A SUBSTITUTE FOR THE TEXT or PARTICIPATION in scheduled class hours. This guide is an aid to organization and review.
Again- PLEASE NOTE: Final Letter Grades will be based on
The SUM the total points from the course exams.
REMEMBER:
This course is Comprehensive.
Zoo 2200
INTRODUCTION
I. Introduction to the fields of anatomy and anatomical terminology.
A. Derivation of the word anatomy
B. Major fields (Fig. 1-1)
1. Gross Anatomy
2. Microscopic anatomy
A) Cytology
B) Histology
3. Neuroanatomy
4. Embryology- Developmental anatomy
C. Anatomical Terminology (Table 1-1,-2)
1. Prefixes
2. Suffixes
3. Anatomical terms used for body parts (Fig. 1-8)
(a few examples)
A) Arm
B) forearm
C) thigh
D) leg
II. Gross anatomical features of the body
A. The anatomical position
1. midline = vertebral column (backbone).
2. bilaterally symmetrical.
3. erect on soles of feet.
4. palms forward.
B. The major planes of sectioning (Fig. 1-10,-11)
1. Sagittal = a vertical plane passing through the object that divides into right & left portions.
A) anterior vs posterior (dorsal vs ventral);
superior vs inferior.
B) midsagittal = equal right & left portions.
2. Frontal or Coronal = a vertical plane passing through the object that divides into anterior (ventral) & posterior (dorsal) portions. It also is at a right angle to the sagittal planes.
at right angles to saggital & frontal planes.
A) anterior vs posterior (dorsal vs ventral); medial vs lateral.
B) In anatomical position, this plane is parallel to the ground.
C. The body cavities (Fig. 1-13,-14)
1. Dorsal cavity
A) cranium (cranial vault).
B) vertebral canal.
2. Ventral cavity
A) Thoracic
1) pleural cavity(s).
2) mediastinum (Fig. 1-14)
a. MIDDLE (pericardium)
b. superior
c. anterior
d. posterior
B) abdominal
1) Subdivisions of the abdominal cavity
a. quadrants.
b. nine regions. (Fig. 1-9)
C) pelvic cavity (NOT bone).
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NOTE: The following information is background material. Any specifics will be discussed when we covered as needed.
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III. Microscopic Anatomy
B. Features of Cells
1. What can be seen with a light microscope
2. Structure of cells as viewed by electron microscopy
A) Nucleus: nuclear membrane, nucleolus, chromatin
B) Cytoplasm: mitochondria, centrioles, endoplasmic reticulum, ribosomes, lysosomes, golgi complex, vacuoles, microvilli, pinocytotic vesicles, cell membrane, cilia, flagella
3. Tonicity
A) isotonic
B) hypotonic
C) hypertonic
4. Processes
A) Passive
1) Diffusion
2) facilitated diffusion
3) osmosis
B) Active
1) active transport
2) endocytosis
a. phagocytosis
b. pinocytosis
3) exocytosis
C. Cell division
1. mitosis
A) karyokinesis
1. prophase
2. metaphase
3. anaphase
4. telophase
B) cytokinesis
2. meiosis = an exact copy of the genetic material is passed on to each daughter cell.
A) karyokinesis
1. prophase I
2. metaphaseI
3. anaphase I
4. telophase II
5. metaphase II
6. anaphase II
7. telophase II
B) cytokinesis
1. spermatogenesis
2. oogenesis
3. Cell cycle
IV. Life Processes
A. Metabolism
1. catabolism
2. anabolism
B. Excitability
C. Conductivity
D. Contractility
E. Growth
F. Differentiation
G. Reproduction
TISSUES
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NOTE: The following types of tissue will be discussed when we cover the systems which contain these tissues.
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I. Levels of organization in living things:
A. cells
B. tissues
1. epithelial
A) simple (one layer)
B) stratified (many layers)
2. connective
A) connective tissue proper
1) areolar
2) adipose
3) reticular
4) dense
5) elastic
A) special connective tissues
1) cartilage
2) bone
3) blood
3. muscular tissue: striated
cardiac
smooth
vascular smooth
4. nervous tissue: neurons
glia
C. organs
D. systems
A. Simple- name based on shape of cell
1. squamous
2. cuboidal
3. columnar
4. pseudostratified columnar
B. Stratified- name based on shape of the cell at the surface.
1. stratified squamous
2. stratified columnar
3. transitional
C. Types of moist membranes composed of epithelial tissues
1. mucous membranes- epithelium
2. serous membranes- mesothelium
3. internal vascular membranes- endothelium
III. Glandular epithelial tissue
A. Definition of a gland
B. two types of glands
1. exocrine
2. endocrine
C. Varieties of exocrine glands
1. merocrine
2. apocrine
3. holocrine
IV. Connective tissue
A. Cell types
1. fibroblasts
2. Adipocytes (fat cells)
3. Mast cells
4. Plasma cells
5. Macrophages
B. Fiber types
1. collagen
2. elastic
3. reticular
C. Fiber arrangements and cell found in connective tissue
1. areolar
2. adipose
3. dense regular
4. dense irregular
5. elastic
6. reticular
Zoo 2200 SKELETAL SYSTEM
I. Functions (Ch. 5)
A. support
B. protection
C. movement
D. hemopoiesis
E. mineral reservoir
II. Structure (Ch. 5 + Ch 3., pp.75-76)
A. types of bone tissue (Fig. 5-1)
1. compact/dense
2. cancellous/spongy
A) marrow cavity
B) trabeculae
C) same mineralization and tissue as dense bone.
via canaliculi.
3. types of bones (Fig. 5-12)
A) long bones
B) short bones- carpals and tarsals
C) flat bones- skull
D) irregular bones- vertebrae
E) sesamoid bones- patella
F) sutural bones
B. parts of (long) bone (Fig. 5-3)
1. diaphysis
A) medullary cavity
B) yellow marrow.
1) hemopoiesis
C) primary ossification center.
2. periosteum
3. endosteum
A) incomplete lining.
4. articular cartilage
5. dense and cancellous bone
6. epiphysis
A) cancellous bone
B) marrow cavity
C) red marrow
D) secondary ossification center
C. Histological Structure (Fig. 5-1)
1. bone tissue
A) periosteum
1) rich blood supply.
B) cellular component- About 2% of bone mass.
1) osteocyte = inactive.
2) osteoblast = bone forming
3) osteoclast = bone resorbing
C) extracellular matrix
1) ground substance = protein + carbohydrates
2) collagen fibers
3) Plate-like crystals of calcium phosphate (hydr- oxyapatite) deposited along collagen fibers.
4) permeated by extensive blood supply.
D) lacunae
1) house osteocytes.
2) canaliculi
a. house/contain osteocyte processes extending between cells.
E) lamellae
1) concentric
a. Haversian system (canal) = osteon
1. parallel to long axis.
b. Volkmann canal
1. connecting between haversian systems and/or nurturing vessels.
2) interstitial
3) circumferential
a. outer
1. deposited by periosteum.
b. inner
1. deposited by endosteum.
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III. Development of bone (Ch.5, p.114)
A. Intramembranous ossification (Fig. 5-4)
bone(hypoxyapatite).
3. blood vessels surround bone collar and penetrate into center of model primary ossification center). Cartilage is replaced (remodelled) by bone.
4. Remodelling increases length as long as cartilage grows (epiphyseal plate).
5. Wall thickens by growing around blood vessels.(Fig.5-7)
6. blood vessels penetrate the metaphysis & carry in osteoblasts.
A) forms secondary ossification center.
6. secondary ossicication centers also increase bone length.
7. All increases in length are due to transformation of the cartilage within the epiphyseal plate.
IV. Divisions (fig. 6-1)
A. Axial skeleton
1. vertebral column
2. ribs (costa)
3. skull (to be studied later)
4. hyoid
5. auditory ossicles
B. Appendicular skeleton
1. Girdles
A) pectoral
B) pelvic
2. Appendages
A) upper
B) lower
V. Axial division
A. skull (presented later)
B. vertebral column (Fig. 6-19)
1. general features
A) centrum/body = weight-bearing region.
B) laminae (paired)
C) pedicles
D) spinous process
1) muscle/ligament attachments.
a. completes posterior wall of vertebral foramen.
E) transverse processes (paired)
1) muscle/ligament attachments.
F) neural arch = A+B+C above.
G) intervertebral disc = amphiarthroses (will be explained later).
1) nucleus pulposus
2) annulus fibrosus
G) articular facets (vary by type of vertebrae).
2. Spinal curvatures (Fig. 6-18)
A) primary (present in fetus)
1) thoracic
2) sacral
B) secondary (change with growth & development)
1) cervical
2) lumbar
C) Abnormal curvatures (pp.159)
1) scoliosis = lateral curve
2) lordosis = lumbar (extension = swayback)
3) kyphosis = thoracic (flexion = hunchback)
3. cervical vertebrae (7) (Fig. 6-20)
A) ALL HAVE TRANSVERSE FORAMINA.
B) unusual vertebrae
1) atlas
a. no body or spinous process.
2) axis
a. odontoid process formed from body & spine of atlas.
4. thoracic vertebrae (12) (Fig. 6-22)
A) 1 - 10 HAVE (SUPERIOR & INFERIOR) DEMIFACETS.
5. lumbar vertebrae (5) (Fig. 6-23)
A) ALL HAVE INTERLOCKING ARTICULAR PROCESSES.
6. sacrum (5) (Fig. 6-24)
A) 5 FUSED VERTEBRAE.
B) base = S1 (widest region)
C) medial sacral crest
1) sacral canal
D) ala (2)
a. fused transverse processes
2) sacral foramina
E) apex
7. coccyx (Fig. 6-24)
A) 3-5 small, fused vertebrae.
C. Rib cage(Fig. 6-22)
1. sternum
A) manubrium
1) jugular notch
B) gladiolus (body)
c) xyphoid process
1) only cartilage.
2. Costa (ribs)
A) vertebrosternal costa (7) (true ribs)
1) costal cartilage connects directly to sternum (#1-7).
B) vertebrochondral costa (3) (false ribs)
1) #8-10 have costal cartilage that connects to #7.
C) vertebral costa (2) (floating ribs)
D) Features
1) head
2) neck
3) tubercle
4) posterior angle
5) shaft
6) costal groove
VI. Appendicular division (Fig. 7-1)
A. Pectoral girdle (Fig. 7-2, Fg. 7-4)
1. clavicle
A) sternal end
B) acromial end
2. scapula (Fig. 7-5)
A) posterior aspect
1) spine of scapula
a. acromion
2) supraspinous fossa
3) infraspinous fossa
B) anterior aspect
1) subscapular fossa
2) coracoid process
C) borders
1) vertebral/medial
2) axillary/lateral
a. glenoid fossa/cavity
3) superior
a. (supra)scapular notch
b. coracoid process
D) Angles
1) superior angle
2) inferior angle
B. Upper extermity (Fig. 7-6)
1. humerus
A) head
B) neck (anatomical)
1) surgical neck
C) greater tubercle
D) anterior aspect
1) proximal epiphysis
a. lesser tubercle
b. intertubercular (bicipital) groove
2) distal epiphysis
a. coronoid fossa
b. capitulum
D) posterior aspect
1) distal epiphysis
a. olecranon fossa
E) deltoid tuberosity
F) lateral epicondyle of the humerus
G) medial epicondyle of the humerus
H) trochlea
2. radius (Fig. 7-7)
A) head
B) neck
C) radial tuberosity
D) styloid process of the radius
E) ulnar notch
1) distal radioulnar joint
3. ulna (Fig. 7-7)
A) olecranon
B) trochlear notch
1) humeroulnar (olecranal) joint
C) coronoid process
D) radial notch
1) proximal radioulnar joint
E) styloid process of the ulna
F) interosseous membrane
4. carpal bones (8) (Fig. 7-8)
A) proximal carpals
1) scaphoid
2) lunateid
3) triquetral (triangluar)
4) pisiform
B) distal carpals
1) trapezium
2) trapezoid
3) capitate
4) hamate
5. metacarpals (5)
6. phalanges (14)
A) digits 2 thru 5
1) proximal phalange
2) middle phalange
3) distal phalange
B) pollex (1st digit) has NO middle phalange.
C. Upper appendage = pectoral girdle + upper extremity.
C. Pelvic girdle = the 2 coxa. (Fig. 7-9, 7-11)
[NOTE: There is NO pelvic BONE.)
1. coxal bone (os coxae) (Fig. 7-10)
A) ilium
1) iliac crest
a. anterior superior iliac spine (ASIS)
b. posterior superior iliac spine (PSIS)
2) iliac fossa
3) arcuate line
4) anterior inferior iliac spine (AIIS)
5) sacroiliac articulation (joint)
a. posterior inferior iliac spine (PIIS)
6) greater sciatic notch
(a. ischial spine)
B) ischium
1) ischial spine
2) ischial tuberosity
3) ischial ramus
C) pubis
1) superior ramus of the pubis
2) pubic symphysis
3) inferior ramus of the pubis
D) acetabulum
E) pelvic brim (Fig. 7-12)
F) pubic arch (subpubic angle) (Fig. 7-13)
1) less than 90 degrees in males.
2) greater than 90 degrees in females.
G) obdurator foramen
2. sacrum (+ coccyx completes pelvis)
A) sacral foramina
B) sacroiliac joint (articulation)
D. Lower extermity (Fig. 7-9)
1. femur (Fig. 7-14)
A) head
B) neck
1) about 125³ degrees
D) lesser trochanter
E) anterior aspect
1) proximal epiphysis
a. greater trochanter
-b. intertrochanteric line-
1) distal epiphysis
a. patellar fossa (surface)
F) posterior aspect
1) proximal epiphysis
a. intertrochantertic crest
b. lesser trochanter
1) distal epiphysis
a. popliteal fossa
b. intercondylar fossa
G) medial epicondyle of the femur
1) medial condyle of the femur
H) lateral epicondyle of the femur
1) lateral condyle of the femur
I) diaphysis
1) lina aspera (posterior aspect)
2. patella (Fig. 7-15)
A) sesmoid bone within quadriceps femoris tendon.
B) (larger) lateral (concave) facet
C) (smaller) medial (concave) facet
D) apex = inferior facing point.
3. tibia (Fig. 7-16)
A) proximal epiphysis
1) medial condyle of the tibia
2) lateral condyle of the tibia
3) intercondylar eminence
4) tibial tuberosity
B) diphysis
1) anterior crest (shin)
2) interosseous crest
C) distal epiphysis
1) medial malleolus
2) fibular notch
4. fibula (Fig. 7-16)
A) head
B) neck
C) interosseous crest
D) lateral malleolus
E) The fibula is NOT weightbearing.
5. tarsal bones (7) (Fig. 7-17)
A) talus
1) articulates with tibia AND fibula.
B) navicular
C) cuboid
D) calcaneous
E) cuniforms (3)
6. metatarsals (5)
7. phalanges (14)
A) digits 2 thru 5
1) proximal phalange
2) middle phalange
3) distal phalange
B) hallux (1st digit) has NO middle phalange.
8. arches of pedal (foot) (Fig. 7-17)
A) lateral longitudinal
B medial longitudinal
C) transverse
E. Lower extermity = pelvic girdle + lower appendage.
VII. Related Clinical Terms or Clinical Briefs
osteomalasia
osteomyolitis
Osteoporosis
osteopenia
osteosarcoma
ostitis
Zoo2200 SKULL
I. Divisions (Fig. 6-2, 6-3)
A. 8 cranial bones = cranium
B. facial (12)
1. 6 considered superficial facial bones
A) lacrimal
B) mandible
C) maxilla
D) zygomatic
E) nasal
F) palatine
C. Foramina (Table 6-1)
II. Cranial bones Fig. 6-7)
A. frontal
1. sinuses
2. supraorbital margin
A) supraorbital foramen/notch
3. frontal squama
B. parietal (paired)
C. temporal (paired) Fig. 6-8)
1. zygomatic process
2. mastoid process
3. styloid process
4. mandibular fossa (diarthrosis)
5. external auditory canal/meatus
6. petrous portion/ridge
A) stylomastoid foramen
B) notch for jugular foramen
C) carotid canal or foramen lacerum
D) petrous portion
1) external auditory canal/meatus
2) tympanic cavity
a. tympanic membrane
b. houses auditory ossicles (to be studied later).
3) inner ear
E) pharyngotympanic/eustacian tube
F) internal auditory canal/meatus
D. occipital (Fig. 6-6)
1. foramen magnum
2. occipital condyles
3. hypoglossal foramen
4. (notch for) jugular foramen
5. superior nuchal line (nuchal crest)
A) external occipital protuberence
E. sphenoid (giant bat) (Fig. 6-9)
1. sella turcica
A) hypophyseal fossa
2. sphenoid sinuses
3. small (lesser) wings
A) optic foramen
4. great wings
A) foramen rotundum
B) foramen ovale
C) foramen spinosum
D) notch for inferior orbital fissure.
5. superior orbital fissure
A. formed by between great & small wings.
6. pterygoid processes
7. notch of internal carotid artery
F. ethmoid (Fig. 6-10)
1. cribiform plate
2. crista galli
3. perpendicular plate (+ vomer = nasal septum)
4. lateral masses (Fig. 6-13)
A) ethmoid sinuses (air cells)
B) superior concha
C) middle concha
G. Cranial fossa (Fig. 6-11)
1. anterior
2. middle
III. Facial bones (Fig. 6-15)
A. inferior nasal conchae (paired) (Fig. 6-10)
B. vomer (Fig. 6-5)
1. completes nasal septum between perpendicular plate of ethmoid and hard palate.
C. lacrimal (paired) (Fig. 6-3)
1. smallest facial bone
2. lacrimal canal
D. nasal (paired) (Fig. 6-3)
E. maxilla (paired) (Fig. 6-3)
1. alveolar process
A) gomphosis
2. (anterior) hard palate
3. maxillary sinuses
4. infraorbital foramen
5. notch for inferior orbital fissure.
F. mandible (Fig. 6-15)
1. ramus
A) condyle
B) coronoid
2. body
A) alveolar process
1) gomphosis
B) mental foramen
1) mandibular canal
G. palatine (paired) (Fig. 6-12)
1. (posterior) hard palate
H. zygomatic (paired) (Fig. 6-15)
1. temporal process
process of zygomatic.
IV. Hyoid bone (Fig. 6-16)
V. Auditory ossicles (paired) (to be studied later).
VI. Bones forming the Nasal Cavity (8) (Fig. 6-13)
(frontal, sphenoid, palatine, maxilla, ethmoid, nasal, inf. n ch., vomer)
VII. Bones forming the Orbital Cavity (7) (Fig. 6-14)
VIII.Bones forming the Oral Cavity (3) (Fig. 6-5)
Zoo2200 ARTHOLOGY
I. Classifications
A. Function (Table 8-1)
1. Synarthroses = no movement
A) sysotoses (suture(s))
1) complete fusion
a. frontal bone (skull)
b. coxal bone
B) gomphosis
C) sychondrosis
2. Amphiarthroses = some movement
A) symphysis (discs)
1. Fibrous Joint = no cavity & no cartilage
A) synarthrosis
1) sutures = skull
2) gomphosis
a. "peg in socket" = teeth
B) amphiarthrosis
1) held together by interosseous ligaments or membranes (syndesmoses).
2. Cartilagenous Joint = no cavity but has cartilage
A) synchondrosis
1) hyaline cartilage is the temporary connecting material between bones (ex. metaphysis)
B) symphysis
1) connects via broad, flat disc of fibrocartilage = symphyses
3. Synovial Joint = has a cavity/capsule & has cartilage
A) diarthrosis (Fig. 8-1)
1) synovial membrane- secretes synovial fluid
a. hyaluronic acid & plasma filtrate
b. contains macrophages.
2) synovial cavity
a. synovial membrane- inside layer
1. does not extend over articular surfaces.
b. fibrous capsule- outside layer
1. ligaments = parallel bundles of fibrocartilage in/around capsule.
3) articular cartilage (hyaline)
a. covers faces of bone, BUT does not connect them.
b. NO perichondrium.
4) Accessory ligaments
a. extracapsular
b. intracapsular
5) example of a synovial joint- the knee (Fig. 8-1)
6) Bursae (p. 208)
a. saclike structures to reduce friction
1. found between a bone & overlaying tissue(s)/structure(s) that would (otherwise) slide directly against the bone.
7) Cartilage- characteristics
a. matrix
1. ground substance = protein + carbohydrates
2. fibers
A. collagen
B. elastic
3. lacunae = spaces within matrix.
A. chondrocytes
1. cartilage altering cells that are (relatively) inactive.
4. NO nerves or blood supply to matrix.
b. cells
1. perichondrium = outer layer of chondroblasts (= cells that are actively altering cartilage).
2. chondrocytes
c. types
1. hyaline
A. most abundent.
B. very flexible and supportive.
2. elastic
A. maintains organ/tissue shape.
3. fibrocartilage
A. NO perichondrium.
B. "mixed" tissue.
B) Types of Synovial joints (Fig. 8-6)
1) hinge
2) pivot
3) gliding
4) ellipsoidal
5) saddle
II. Types of Motion/Movement (Fig. 8-3, -4, -5) (17 types)
A. flexion vs extension
B. adduction vs abduction
C. circumduction
D. rotation
E. pronation vs supination
F. inversion vs eversion
G. dorsiflexion vs plantar flexion
H. opposition
I. protraction vs retraction
III. Related Clinical Terms or Clinical Briefs
rheumatism shoulder separation
fibrosis arthritis
polio osteoarthritis
subluxation slipped disc
sciatica herniated disc
bursitis carpal tunnel syndrome
arthroscopic surgery sprain
continuous passive motion (CPM)
Zoo 2200 MUSCULAR SYSTEM
MYOLOGY
I. Chief Function : Contraction- necessary for any form of movement.
helps in temperature regulation.
II. Characteristics
A. Excitability
B. Contractility
C. Extensibility
D. Elasticity
III. Types (Fig. 3-19)
A. Skeletal: striated, voluntary, multinucleated muscle fibers
B. Cardiac: striated, involuntary, individual cells, 2-5 nuclei/cell, intercalated discs
C. Smooth: nonstriated, involuntary, individual fusiform cells, single nucleus
D. Vascular: nonstriated, involuntary, individual fusiform cells, single nucleus
IV. Structural characteristics of skeletal muscle (Fig. 9-1)
A. Parts
1. belly
2. tendon
A) origin
B) insertion
C) aponeurosis- a broad, flat tendon
B. Arrangement of muscle fibers in the belly (Fig. 10-1)
1. parallel
A) fusiform
B) bicipital
3. convergent (triangular or radiate)
4. pennate
A) uni-, bi-, multipennate
5. circular or sphincter
C. Histological organization (Fig. 9-4)
1. belly
A) epimysium
2. fasciculi
A) groups of muscle cells with common acyion.
B) perimysium
3. (individual) muscle cell(s)
A) endomysium
4. Subdivisions of a muscle fiber (Fig. 9-4)
A) initially formed by the fusion of several cells.
B) muscle fiber contains myofibrils
C) myofibrils contain sarcomeres attached end-to-end.
D) sarcomeres contain myofilments (Fig. 9-6)
1) (thick) myosin filaments (Fig. 9-5)
2) (thin) actin filaments
3) position of filaments during contraction & relaxation
4) sarcomere regions (Fig. 9-6)
a. (light) I band
b. (dark) A band
c. Z line
E) sarcoplasmic reticulum (SR) (fig. 9-10)
1) transverse tubules
a. parallel Z-lines (mammalian)
2) lateral sacs- larger tubules of SR paralleling Z- line.
3) relationship of this arrangement to nerve stimulation (Exh. 9.1).
4) Parts of a myoneural junction (Fig. 9-11, 9-12)
A) nerve impulses travel 'down' nerve fiber.
B) stimulus passes to muscle cell via release of chemicals (neurotransmitters) at the nerve terminal.
C) stimulus travels to myofibrils via channels in sarcoplasmic reticulum.
V. Varieties of movement of skeletal muscle
A. see Skeletal System, II, Types of Movements (p, 23 in this guide).
B. Actions
1. agonists = prime mover
A) synergist
2. antagonist
VI. Head and Neck Muscles
A. Muscles of facial expression (Fig. 10-6, Table 10-2)
1. orbicularis oris
2. orbicularis oculis
3. epicranius
A) frontalis + aponeurosis + occipitalis
4. platysma
5. buccinator
6. depressor labii inferioris
7. levator labii superioris
B. Extrinsic Eye Muscles (Fig. 10-9)
1. superior rectus
2. inferior rectus
3. medial rectus
4. lateral rectus
5. superior oblique
6. inferior oblique
B. Muscles of Masticulation (Fig. 10-10)
1. temporalis
2. masseter
3. pterygoids
4. buccinator
C. Muscles of the Tongue (Fig. 10-11)
1. genioglossus
2. styloglossus
3. palatoglossus
4. hyoglossus
D. Muscles of the Pharynx (Fig. 10-12)
1. constrictors
2. laryngeal elevators
3. palatal muscles
E. Muscles of the (Anterior) Neck (Fig. 10-13)
1. digastric
2. mylohyoid
3. stylohyoid
4. geniohyoid
5. thyrohyoid
6. sternothyroid
7. sternohyoid
8. omohyoid
(9. sternocleidomastoid)
VII. Trunk Muscles
A. Muscles that move the head and vertebral column
1. Flexors (some also rotate or laterally bend the trunk and head) (Fig. 10-14, 10-15)
A) sternocleidomastoid (Fig. 10-14)
B) longus capitis
C) scalenes
D) longus coli
B) rectus abdominus (Fig. 10-15)
C) external oblique
1) rotate & lateral flex
D) quadratus lumborum
1) primary side flexor of lumbar vertebrae.
E) internal oblique
1) rotate & medial flex
F) transversus abdominus
2. Extensors (some also rotate or laterally bend the trunk and head) (Fig. 10-14)
A) spinalis group
1) splenius
2) semispinalis capitis
B) longissimus group
1) capitis
C) iliocostalis group
2) thoracis
3) lumborum
D) multifidius
B. Muscles of the rib cage (Fig. 10-15)
1. external intercostals (contracts during inspiration)
2. diaphragm (contract during inspiration) (Fig. 10-16)
3. internal intercostals (contracts during forced expiration)
4. serratus posterior (contracts during forced expiration) (Fig. 11-1)
C. Muscles of the perineum-pelvic diaphragm (Fig. 10-17)
1. urogenital triangle
A) urogential diaphragm
1) deep transverse perineal muscles.
B) transverse perineals
1) borders urogential diaphragm.
2) between ischial tuberosities & central tendon.
C) ischiocavernosus
1) along ischial ramus.
D) bulbocavernosus
1) into base of penis or surrounds vaginal openning.
2. anal triangle
A) levator ani origin- ischial spine (iliococcygenus) + ramus of pubis (pubococcygeus)
insertion- coccyx + median raphe
pubis/clitoris
1) coccyx <
central tendon
B) coccygeus origin- ischial spine
insertion- coccyx + lower sacrum
C) external anal sphincter
VII. Muscle of the upper limb (may need to know origins and insertions)
A. Stablizers of the scapula (Fig. 11-1,-2,-3, Table 11-1)
1. trapezius: origin- occipital bone, ligamentum nuchae,
spine of C7 & T1-12
insertion- lateral third of clavicle, acromion, spine of scapula
2. rhomboids: origin- spines of C7-T5
insertion- vertebral border of scapula below spine
3. levator scapulae: origin- transverse processes of C1-C4
insertion- vertebral border of scapula over spine
4. serratus anterior: origin- exterior of ribs 1-9
insertion- anterior surface of entire 5. pectoralis minor: origin- anter. surface of ribs 3-5
insertion- coracoid process
6. subclavius: origin- 1st rib
insertion- inferior clavicle
complements pec. minor
B. Movers of the humerus (Fig. 11-5, Table 11-2)
1. axial skeleton
clavicle, sternum, costal cartilages of ribs 1-6, aponeurosis of external oblique
insertion- greater tubercle
B) latissimus dorsi: origin- spines of T6-T12, L1-L5, dorsal sacrum, posterior iliac crest
insertion- medial margin of intertubercular groove.
2. scapula
A) deltoid: origin- lateral third of clavicle, acromion & spine
insertion- deltoid tuberosity
insertion- shaft of humerus
B) coracobrachialis: origin- coracoid process
insertion- shaft of humerus
3. Muscles of/at the glenohumeral joint
A) musculotendinous cuff (Fig. 11-5, Table 11-2)
1) supraspinatus: origin- supraspinatus fossa
insertion- superior aspect of greater tubercle
2) infraspinatus: origin- infraspinatus fossa
insertion- greater tubercule (inferior to supraspinatus)
3) teres minor: origin- dorsal surface of axillary border
insertion- greater tubercule (inferior to infraspinatus)
4) subscapularis: origin- subscapular fossa
insertion- lesser tubercle
angle
insertion- lesser tubercle
C. Movers of the Radius and Ulna (Fig. 11-7, Table 11-3)
1. flexors (Fig. 11-7)
A) biceps brachii: origin- glenoid & coracoid process insertion- radial tuberosity
B) brachialis: origin- anterior surface of distal shaft of humerus
insertion- coronoid process of ulna
C) brachioradialis: origin- infraglenoid tuberosity, posterior surface of humerus.
insertion- styloid process of radius.
2. supinators (Fig. 11-7)
A) supinator: origin- lateral epicondyle of humerus and proximal ulna.
insertion- proximal radius
B) biceps brachii: origin- glenoid + coracoid process.
insertion- radial tuberosity
3. pronators (Fig. 11-7)
A) pronator teres: origin- medial epicondyle of humerus, coronoid process of ulna.
insertion- middle shaft of radius.
B) pronator quadratus: origin- mediodistal anterior ulnar shaft
insertion- laterodistal anterior radial shaft
4. extensors (Fig. 11-8)
A) triceps brachii: origin- infraglenoid tuberosity, & posterior surface of shaft of humerus.
insertion- olecranon process of ulna.
B) anconeous: origin- lateral epicondyle of humerus.
insertion- olecranon & prox. shaft of ulna.
D. Forearm muscles that move the wrist, fingers and thumb
1. Wrist flexors: origin- med. epicondyle of humerus (Fig.11-7)
insertion- carpals and palmar aponeurosis.
A) palmaris longis
B) flexor carpi radialis- insertion = styloid process of radius
C) flexor carpi ulnaris- insertion = styloid process of ulna
2. wrist extensors: origin- lateral epicondyle of humerus
insertion- metacarpals (Fig. 11-8,-9)
A) extensor carpi radialis
B) extensor carpi ulnaris
3. flexors of the digits (Table 11-4)
A) flexor digitorum superficialis: (Fig. 11-7,-9,-11)
origin- medial epicondyle of humerus, coronoid process
of ulna, anterior surface of radius
insertion- ant. surface of base of mid. phlanges 2-5
B) Flexor digitorum profundus: (Fig. 11-7,-9)
origin- medial epicondyle of humerus, coronoid process and anterior surface of ulna
insertion- ant. surface of base of dist. phalanges 2-5
C) flexor pollicis longus: (Fig. 11-7,-9)
origin- anterior surface of radius
insertion- base of distal phalanx of thumb
4. extensors of digits (Table 11-4)
A) extensor digitorum commonis: (Fig. 11-8,-9,-11)
origin- lateral epicondyle of humerus
insertion- posterior surface of phalanges 2-5
B) extensor digiti minimi:
origin- extensor digiti commonis tendon
insertion- extensor digitorum tendon on posterior of little finger
C) extensor indicis: origin- posterior surface of distal ulna/radius
insertion- ext. digitorum's tendon on post. of index finger
D) extensor pollicis longus:
anterior & medial
origin- posterior surface of radius
insertion- base of distal phalanx of thumb (most medial & anterior tendon of "snuff box").
E) extensor pollicis brevis:
origin- posterior surface of radius
insertion- base of proximal phalanx of thumb (lateral tendon of "snuff box")
F) abductor pollicis longus:
origin- posterior surface of radius & ulna
insertion- base of first metacarpal (under ext. pollicis brevis)
E. Intrinsic muscles of the hand (origins & insertions need not be memorized, but know actions) (Fig. 11-12, Table 11-5)
1. thenar muscles: abduct, adduct, flex, and give opponent movement to the thumb
A) adductor pollicis brevis
B) flexor pollicis brevis
2. hypothenar muscles: adduct, flex, and give opponent movement to little finger
A) opponens digiti minimi
B) flexor digiti minimi
C) abductor digiti minimi
3. midpalmar muscles
A) interossei: extend interphlangeal joints;
abduct (dorsal) & adduct (palmar) fingers from or to middle finger.
B) lumbricals: flex metacarpophalangeal joints
IX. Muscles of the lower extermity (origins and insertions)
A. Movers of the femur (Fig. 11-12, Table 11-6)
1. flexors (Fig. 11-14)
A) iliopsoas: origin- transverse processes of T12-L5, iliac crest and fossa
insertion- lesser trochanter
B) pectineus: origin- pubis
insertion- posterior surface of femur below lesser trochanter
C) tensor fasciae latae: (Fig. 11-13)
origin- anterior iliac crest and anterior superior iliac spine
insertion- iliotibial band
2. adductors of the thigh (medial compartment): (Fig. 11-14)
origin(s)- on pubis and ischium
insertion- linea aspera of femur <A) pectineus>
B) adductor magnus- entire length of femur
C) adductor brevis- proximal femur
D) adductor longus- middle femur
E) gracilis: origin- pubis symphysis
insertion- on medial tibial tuberosity
(hip & knee flexor)
3. extensors (Fig. 11-13)
A) gluteus maximus: origin- outer surfaces of ileum, sacrum and coccyx
insertion- lateral surface of greater trochanter
B) gluteus medius: origin- outer surface of ilium
insertion- lateral surface of greater trochanter
C) gluteus minimus: origin- outer surface of ilium
insertion- anterior surface of greater trochanter
4. lateral rotators of the thigh:
origins- in and around the obturator foramen
insertions- on the greater trochanter
A) piriformis
B) obdurator internus & externus
C) quadratus femoris
B. Movers of the tibia and fibula (Table 11-7)
1. anterior compartment (Fig. 11-13)
A) quadriceps femoris
1) rectus femoris:
origin- anterior inferior iliac spine
2) vastus lateralis:
origin- greater trochanter & lateral aspect of linea aspera
3) vastus medialis:
origin- medial lip of linea aspera
4) vastus intermedius:
origin- anterior surface of femur
5) All bellies insert on the tibial tuberosity via the patella and the patellar ligament.
B) sartorius: origin- anterior superior iliac spine
insertion- medial proximal tibia
2. posterior compartment (Fig. 11-7)
A) biceps femoris: origin- ischial tuberosity and lateral edge (post.) of linea aspera
insertion- lateral head of fibula and lateral condyle of tibia
B) semitendinosus: origin- ischial tuberosity
insertion- medial proximal tibia
C) semimembranosus: origin- ischial tuberosity
insertion- medial proximal tibia
C. Muscles that move the ankle and toes (Table 11-8)
1. anterior compartment (Fig. 11-2)
A) tibialis anterior:
origin- inferior to & anterior to the lateral condyle and proximal shaft of tibia
insertion- anterior tarsals & 1st metatarsal
B) extensor digitorum longus:
origin- lateral condyle of tibia, ant. of fibula
insertion- superior surfaces of phalanges 2-5
C) extensor hallucis longus:
origin- anterior surface of fibula
insertion- post. surface of distal phalanx in great toe
D) peroneous tertius:
origin- fibula + ext. digit. longus
insertion- 5th metatarsal + tarsal bones
2. lateral compartment (Fig. 11-20)
A) peroneus longus:
origin- proximal 2/3 of lateral fibula
insertion- inferior surface of first metatarsal and med. cunieform
B) peroneus brevis: origin- distal 2/3 of fibula
insertion- lateral side of fifth metatarsal
3. posterior compartment (Fig. 11-18)
A) gastrocnemius:
origin- superficial & posterior aspect of medial & lateral epicondyles of femur
insertion- calcaneous via Achilles tendon
B) plantaris: origin- medial epicondyle of femur
insertion- Achilles tendon
C) soleus: origin- posterior surfaces of tibia and fibula
insertion- calcaneous via Achilles tendon
D) flexor digitorum longus:
origin- posterior surface of tibia
insertion- distal phalanx of toes 2-5
E) tibialis posterior: origin- posterior surfaces of tibia and fibula
insertions- posterior tarsals and metatarsals 2-4
F) flexor hallucis longus:
origin- lower 2/3 of fibula
insertion- distal phalanx of great toe
G) popliteus: origin- lateral epicondyle of the femur
insertion- medial proximal tibia
D. Intrinsic muscles of the foot (origins and insertions = no; actions = yes) (Fig. 11-22, Table 11-9)
1. extensor digitorum brevis & extensor hallucis brevis extend the toes & great toe.
2. flexor digitorum brevis- flexes toes 2-5
(It inserts on middle phalanx & has a split tendon to allow flexor digitorum longus to insert on distal phalanx.)
VIII. Related Clinical Terms or Clinical Briefs
compartment syndrome bursitis
sprains strains
tendinitis carpal tunnel syndrome
ischemia
Zoo 2200 HEMATOLOGY
I. Main functions (Table 20-1)
A. Transport oxygen and carbon dioxide.
to all of the 75 trillion cells in body.
B. Transport food materials.
C. Transport waste products.
D. Transport hormones.
E. Regulates acidity of body tissue fluids.
F. Aids in the regulation of body temperature.
G. Aids in the regulation of body water content.
H. Contains macrophages and antibody producing cells for disease resistance.
II. Characteristics of blood (Fig. 20-1, Table 20-2)
A. Blood volume in males (5-6 liters) vs females (4-5 liters)
1. 55% = plasma
2. 45-6% = formed elements
B. Liquid component- plasma (Fig. 20-1)
1. water - 92%
2. solutes - 8%
A) plasma proteins
1) albumins - viscosity and osmolarity, 55-60%
2) gamma proteins - contain antibodies, 33-8%
3) fibrinogen - aids in clotting, 7%
B) metabolites/nutrients
1) lipids
2) glucose
3) amino acids
4) nitrogen wastes
C) electrolytes
1) HCO3 ions
a. pH buffer
C. Formed elements- "Blood cells" (Table 20-3)
1. complete blood count (CBC) = measures hemoglobin content, number of RBCs, number & % of leukocytes, and cell morphology.
2. erythrocytes (RBCs) (5,200,000/ml) (Fig. 20-2)
A) formed in red bone marrow
B) non-nucleated
C) contain hemoglobin which carries oxygen
D) hematocrit (Hct) = percent of blood that is
erythrocytes.
1) males = 40-54.
2) females = 37-47.
3. leukocytes (6-9000/ml) (Fig. 20-5)
A) differential count = number of each leukocyte per 100 leukocytes.
B) granular leukocytes or granulocytes
1) All have lobulated nuclei.
2) prominent lysosomal granules in cytoplasm.
3) Formed in red bone marrow.
phagocytosis of foreign materials.
5) basophils (<1%; 0-150ul)
a. release histamine.
1. increase inflammation.
2. chemotaxis
b. concerned with Ag/Ab interactions.
c. phagocytosis related to processing AGs.
6) eosinophils (2-3%; 0-700ul)
a. participate in antibody/antigen interactions.
b. involved in allergic responses.
c. phagocytosis related to processing AGs.
C) agranular leukocytes
1) monocytes (6%; 200-950ul)
a. large cells with horseshoe shaped nucleus.
b. formed in red bone marrow.
c. true macrophages (phagocytic).
1. chemotaxis.
2) lymphocytes (30%; 1500-4000ul)
D) platelets (350,000/ml)
1) formed in red bone marrow.
2) cytoplasmic fragments of megakarocyte.
3) important in thrombogenesis.
4. Site(s) of action of leukocytes, erythrocytes, and platelets.
___
5. Origin of blood cells (hemopoesis). The source of (all) cell types are stem cells = hemocytoblasts (Fig. 20-8)
A) lymphoblast > lymphocyte.
B) monoblast > monocyte.
C) promyelocyte > granular leukocyte.
D) promegakarocyte > > thrombocytes (platelets).
E) erythroblast -> normoblasts -> reticulocyte -> erythrocyte. This = erythropoesis.
1) 33% of cell = hemoglobin (Hgb). (Fig. 20-3)
2) four heme groups
a. each contains an atom of iron (FE).
(O-O).
3) globin = protein molecule.
4) picks up O2 in lungs; releases O2 in tissues.
5) breakdown products of hemoglobin.
a. heme group
1. bilirubin (eliminated in bile)
2. iron (stored for reuse).
b. globin
1. broken down by macrophages.
___
D. Blood typing systems (Fig. 20-4)
1. Based on presence of ANTIGENS (Ag) or agglutinogens on plasma membranes of the RBCs. An antigen is a protein that will generate the production of an ANTIBODY (Ab).
2. ANTIBODIES or agglutinin are found in the blood plasma, as circulating gamma globulins (proteins). One does not have agglutinins against the type(s) of agglutinogens ones synthesizes (ie, one(s) found your RBCs), BUT one does synthesize agglutinin (Abs) against any of the OTHER agglutinogens (Ags).
A) type A = only A agglutinogen on RBCs. Therefore, has B agglutinins in plasma.
B) type B = only B agglutinogen on RBCs. Therefore, has A agglutinins in plasma.
C) Type AB = A & B agglutinogen on RBCs. Therefore, has no (AB) agglutinins in plasma.
D) type O = NO agglutinogen on RBCs. Therefore, has A and B agglutinins in plasma.
4. Rh system: (Rh refers to Rhesus monkey, were this Ag was first found.
A) Rh+ = have Rh agglutinogen on RBCs.
B) Rh- = NO Rh agglutinogen on RBCs.
C) Normally, there are NO geneticly determined anti-Rh agglutinins in human plasma. However, if an Rh- person comes in contact with RH+ blood, they produce Rh agglutinins (sensitized Rh-). A second contact with Rh+ blood will produce a reaction, possibly severe.
1) erythroblastosis fetalis. (Rh+ fetus in Rh- mother)
2) treat with anti-Rh gamma2-globulin agglutin preparation immediately after partuition or abortion.
a. binds Rh+ agglutinogens before mothers immune system can respond effectively.
III. Related Clinical Terms or Clinical Briefs (p. 517-9)
anemia - a symptom.
drop Hgb or RBCs = fatigue, pale, low cold resistance
hemorrhagic anemia - volume loss normovolemic
hemolytic anemia - ghosts, ruptured RBCs hemophilia
aplastic anemia - none, not produced thrombus
sickle cell anemia - shape change erythrocytosis
pernicious anemia – poor nutrition
polycythemia - increased numbers, p.508
leukemia - "cancer of blood" , p.512. accelerated production of WBCs.
blood doping- p. 515
transfusion
Zoo 2200 RESPIRATORY SYSTEM
I. Thorax
A. Rib cage
1. "bucket handles". (Fig. 24-14)
B. Intercostal muscles
1. external
2. internal
C. Thoracic spaces (Fig. 24-13)
1. "sealed bags"
2. pleura (2) (Fig. 24-11)
A. contain lungs
B. pleural linings
A) visceral
B) parietal
C) fluid-filled pleural cavity between the 2 layers.
3. mediastinum
A) volume not occupied by lungs
B) heart = middle mediastinum
1) middle mediastinal linings
a. visceral
b. parietal
c. fluid-filled pericardial cavity between 2 layers.
D. superior mediastinum
E. posterior mediastinum
F. anterior mediastinum
II. Functions of the Respiratory System
A. Transport of air from outside.
Provide a surface for the exchange of oxygen & carbon dioxide.
B. The movement of air allows vocalizations.
C. Inhaled air provides sensory stimuli picked up by the olefactory epithelium.
D. 3 processes
1. pulmonary ventilation = breathing
A) inspiration
B) expiration
2. external respiration
3. internal respiration
E. Mechanics of breathing (Fig. 24-14)
1. Muscles of inspiration
A) external intercostals
B) diaphragm
allows air from outside to rush in.
3. muscles of expiration
4. When expiratory muscles contract and (inspiratory muscle relax), chest cavity volume decreases. This increases
thoracic air pressure, which forces air from the inside to rush outside.
5. total lung capacity
A) tidal volume (500 ml)
1) eupnea
B) inspiratory reserve volume (3000 ml)
C) expiratory reserve volume (1200 ml)
D) residual volume (1200 ml)
E) vital capacity
1) tidal volume + inspiratory reserve
volume + expiratory reserve volume
F) functional residual capacity
1) expiratory reserve volume + residual
volume
G) total lung capacity
1) vital capacity + residual volume
III. General features of the respiratory system (Fig. 24-2)
A. Pathway of air into lungs: nasal cavity
pharynx
larynx
trachea
primary bronchi
lungs
B. The nasal cavity (fig. 22-2)
1. lined with pseudostratified ciliated columnar epithelium.
Fig. 24-2 & -3
2. contains the olefactory epithelium (see also nervous system notes).
3. external nares
4. nasal cavity
A) perpendicular plate
B) concha
1) superior
2) middle
3) inferior
5. internal nares
C. nasopharynx (Fig. 24-3)
1. lined with pseudostratified ciliated columnar epithelium.
2. contains the pharyngeal tonsils.
3. contains opening to the eustachian tube(s).
D. oropharynx
1. lined with stratified squamous epithelium.
2. contains the lingual and palatine tonsils.
E. laryngopharynx
1. lined with stratified squamous epithelium.
2. contains openings to the larynx and esophagus.
F. structure & function of the larynx (Fig. 24-4, -5)
1. unpaired cartilages
A) epiglottis
B) thyroid
C) cricoid
2. paired cartilages
A) arytenoids
B) corniculate
C) cuniform
3. glottis
4. ventricular folds (false vocal cords)
5. vocal folds (true vocal cords)
6. Laryngeal musculature
A) extrinsic
B) intrinsic
G. gross anatomical features of the lungs
1. the pleura (see II. Thorax above)
2. right lung:
3 lobes- upper, middle, & lower
3. left lung:
2 lobes- upper & lower
4. 10 bronchiopulmonary segments per lung (Fig. 24-10):
a. right lung = superior lobe = 1-3
middle lobe = 4-5
lower lobe = 6-10
b. left lung = superior lobe = 1-5
inferior lobe = 6-10
___
5. mediastinal surface features of the right lung
A) groove for the Azygos vein
B) openings for pulmonary vessels and right primary bronchus in hilus
6. mediastinal surface features of the left lung
A) groove for aorta
B) openings for pulmonary vessels and left pulmonary bronchus
C) contains the cardiac notch and cardiac impression to make room for the heart.
___
H. The respiratory tree
1. trachea (Fig. 24-7)
A) tube supported by cartilagenous rings
B) lined with pseudostratified columnar epithelium
C) branches to each lung = primary bronchi.
(Fig. 24-10)
1) plates of cartilage
D) branch to each lobe = secondary bronchus.
1) right lung- 3 secondary bronchi
2) left lung- 2 secondary bronchi
E) branch to each bronchopulmonary segment = tertiary bronchus. (Fig. 24-10)
1) each tertiary bronchus ramifies to functionally independent units within the lungs.
2) 10 segments per lung:
a. right lung- superior lobe 1-3
middle lobe 4-5
lower lobe 6-10
b. left lung- superior lobe 1-5
inferior lobe 6-10
2. Tertiary bronchi get progressively smaller, becoming bronchioles (lack cartilage). Bronchioles ultimately give rise to 6500 terminal bronchioles. Branches of these give rise to respiratory bronchioles.
3. Respiratory bronchioles (Fig. 24-11)
A) Last (most distal) of bronchiole branches.
B) First presence of alveolar sacs project off its walls.
4. Alveolar ducts (Fig. 24-11, -12)
A) surrounded by smooth muscle fibers with no
cartilagenous supports to keep the lumen open.
B) simple cuboidal epithelial lining and some goblet cells.
C) each alveolar duct opens into a group of alveoli.
5. The alveoli make up the respiratory portion of the lung. Are about 150 million per lung. (Fig.24-11)
A) Type I alveolar epithelial cells
1) simple squamous epithelium.
2) part of alveolar membrane
B) Type II alveolar epithelial cells
1) secrete pulmonary surfactant to reduce surface tension.
C) each alveolus is surrounded by a network of capillaries.
D) pathway of a carbon dioxide molecule OUT of lungs:
(Fig. 24-12)
1) blood plasma
2) capillary wall & basement membrane
3) extracellular space (if any)
4) alveolar wall & basement membrane
5) pulmonary surfactant
6) lumen of alveolus
E) pathway of an oxygen molecule INTO blood:
1) lumen of alveolus
2) pulmonary surfactant
3) alveolar wall & basement membrane
4) extracellular space (if any)
5) capillary wall & basement membrane
6) blood plasma
7) plasma membrane of erythrocyte
___
J. Neural Control
1. Medullary rythmicity area
A) sets basic rythum of respiration.
B) inspiratory area/center
1) generates controlling nerve activity
for eupnea.
2) intrinsic activation following expiration.
3) expiration is passive.
C) expiratory area/center
1) inactive except during forced expiration.
2) expiratory area activated by increased
activity of inspiratory area.
2. Apneastic area
A) lower Pons
B) stimulates inspiratory area to prolong inspiration.
C) is overidden by pneumotaxic area.
3. Pneumotaxic area
A) upper Pons
B) continuously innervates inspiratory area.
1) helps to terminate inspiratory phase of
respiration.
___
III. The Hemlich Maneuver (p. 606)
A. Learn to do it.
B. DO NOT USE BACK BLOWS.
1. This ACTUALLY will suck the foreign body DEEPER into the lungs.
C. DO NOT USE Chest Thrusts.
1. Enough force to be effective will break ribs and puncture lungs.
IV. Related Clinical Terms or Clinical Briefs (p. 621-3)
bronchial asthma pulmonary embolism
bronchitis corysa
emphysema influenza
pneumonia pleuritis
tuberculosis cystic fibrosis
asphyxia aspiration
dyspnea eupnea
hypoxia
pneumothorax hemothorax
Zoo 2200 CARDIOVASCULAR SYSTEM
I. General Scheme of Circulation (Fig. 21-1, 22-8)
A. Arteries and veins are united by connecting capillary beds.
B. Pulmonary Circulation: blood leaves from right ventricle, through the pulmonary arteries to the lungs, and returns to left atrium. All capillaries gain oxygen. (Fig. 22-9)
C. Systemic Circulation: blood leaves from left ventricle, through the aorta to body tissues, and back to the right atrium. All capillary beds lose oxygen.
D. Anastomoses: direct communication between arteries and/or veins without an intervening capillary bed. (Fig. 22-4)
E. Structure of blood vessels. (Fig. 22-1,-2)
1. Arteries- ANY vessel that conveys blood AWAY from the heart.
A) tunica externa (adventitia)- connective tissue & nerves.
B) tunica media: relatively thick (vascular) smooth muscle layer & elastic fibers.
1) elastic arteries
2) muscular arteries
C) tunica interna (intima)
1) endothelium
2) internal elastic lamina
D) Smallest branches (arterioles) are equipped with "precapillary sphincters" to regulate blood flow to various capillary beds.
2. Veins- ANY vessel that conveys blood TOWARD the heart.
A) tunica externa
B) tunica media: (vasc) smooth muscle layer is thinner than in arteries.
C) tunica interna
1) endothelium
a. endothelium has valves
2) internal elastic lamina
D) blood reservoir(s) = 65-70% in venous system. (Fig. 22-7)
1) arteries = 13%
2) capillaries = 7%
3) heart = 7%
4) pulmonary circulation = 13%
3. Capillaries
A) Wall is a single-cell-thick endothelial layer
B) Thin wall allow materials to diffuse into and out of blood.
C) Types (fig. 14.3)
1) continuous (true)
a. most
2) fenestrated
a. intestinal villi
b. kidneys
c. endocrine glands
3) sinusoids
a. liver
b. spleen
c. adenohypophysis
4. Vasa vasorum (p. 544)
II. Structure and function of the heart (Fig. 21-4)
A. Location in the mediastinum (Fig. 21-2)
B. The pericardium (Fig. 21-2)
1. outer layer of thick fibrous connective tissue.
2. innermost layer of epithelial cells (parietal pericardium).
3. fluid-filled pericardial cavity between parietal pericardium and the visceral pericardium (see below).
C. The heart wall (Fig. 21-3)
1. epicardium (visceral pericardium)
2. myocardium: much thicker in ventricles than in atria.
3. endocardium
A) endothelium
B) subendothelial cushion = loose connective tissue & purkinje fibers.
D. Circulation through the 4 chambers of the heart. (Fig. 21-5,-7)
R & L atria, R & L ventricles, interventicular septum
1. See flow chart for the adult (know valves well) (Fig. 21-5)
A) atrioventricular valves
1) between each atrium and ventricle.
2) papillary muscles
3) cordae tendinae
B) semilunar valves
1) between each ventricle and draining artery.
E. Heartbeat initiation and regulation (Fig. 21-10, p. 533)
1. ANY cardiac cell can initiate its own or its neighbor's contraction.
2. specialized cardiac muscle cells in the sino-atrial (SA) node normally initiate rhythmic contractions about 70-80 times/minute.
3. The impulse spreads from cell to cell throughout both atria so they can contract together.
4. Next the impulse spreads to the ventricles via the atrioventricular (AV) node and the Purkinje fibers. Both ventricles contract together shortly after atrial contraction.
A) cardiac muscle organization & contraction.
5. Both sympathetic and parasympathetic nerve fibers influence the rate of contraction.
____
F. Control mechanism
1) autonomous- sympathetic fibers => accelerator/stimulator
parasympathetic fibers => inhibitor
2) In medulla are =
A) (CAC) cardioacceleratory center
1. Acceleratory center -> (cardiac nerves) out ventral root of spinal nerve -> SA/AV node(s) and myocardium.
B) (CIC) cardioinhibitory center
1. baroreceptors -> Sensory nerve (afferent) to inhibitory center via cranial nerves IX and X- efferent information out X (vagus) to nodes.
C) controlled by hypothalamus -> by cerebrum
3. temperature
4. age
5. sex
6. emotions
___
angioplasty faulty conduction
aneurysm myocardial infarction
atherosclerosis bradycardia
hypertension tachycardia
carditis cardiac arrythmias
ischemia angina pectoris
III. Circulatory routes to supply body tissues (Fig. 21-4, -8)
A. Coronary (Cardiac) Circulation (FIG. 21-8 )
Vessels to the heart: coronary arteries
cardiac veins
1. blood leaves ascending aorta (at semilunar valves) to enter two cardiac supply vessels.
A) Left coronary runs under left atrium, giving rise to:
1) circumflex branch/artery
a. supplies anterior & lateral Left ventricles & Left atrium.
2) anterior interventricular branch/artery
a. supplies anterior Right and Left ventricles.
B) Right coronary artery runs under right atrium, giving rise to:
1) marginal branch/artery
a. supplies posterior & lateral Right ventricles.
2) posterior interventricular branch/artery
a. supplies posterior Right and Left ventricles.
C) Venous return
1) Great cardiac vein
a. drains anterior and left heart
2) Middle cardiac vein
a. drains posterior heart
3) Small cardiac vein
a. drains right heart
4) All merge and drain (small and middle) or drain into Coronary sinus.
B. Pulmonary Circulation
C. Systemic Circulation
1. Systemic Arteries (Fig. 22-10)
A) the Aorta (Fig. 22-15, -20)
1) branches
a. thorax & upper extremity (Fig. 22-12)
b. neck (Fig. 22-13)
c. head (Fig. 22-14)
d. paired branches to the abdomen (Fig. 22-15)
e. unpaired branches to the abdomen (Fig. 22-17)
f. pelvic and perineum (Fig. 22-15,-16,-17)
1. Most organs are supplied by branches of the internal iliac.
2. Rectal arterial supply: middle sacral and inferior mesenteric branches supply superior part. Inferior iliac branches supply inferior part.
g. lower extremity (Fig. 22-18,-19)
2. Systemic Veins (Fig. 22-21)
A) Superior vena cava ((Fig. 22-23)
1) branches
a. thorax & upper extermity (Fig. 22-23)
b. neck & head (Fig. 22-22)
B) Inferior vena cava (Fig. 22-23)
1) branches
a. paired branches to the abdomen (Fig. 22-15)
b. unpaired branches to the abdomen (Fig. 22-15)
C) Hepatic Portal Circulation (Fig. 22-26)
D) lower extermity (Fig. 22-25)
VI. Related Clinical Terms or Clinical Briefs
arteriosclerosis aneurysm
pericarditis thrombus
patent foramen ovale or ductus arteriosis
pulmonary embolism
Schematic Summary of the Systemic Arteries
HEART
ASCENDING AORTA (capitalized = elastic arteries)
Coronary arteries
AORTIC ARCH
BRACHIOCEPHALIC
R. internal carotid Circle of Willis
R. COMMON CAROTID
R. external carotid
à facial/neck arteries
Humoral circumflex a's.
Radial
R. SUBCLAVIAN à Axillary à Brachial Palmar arches à digital a's.
Ulnar
R. vertebral
R. thyrocervical
à suprascapular à humoral circumflex a's.R. internal thoracic
à ant. intercostal a's.R. costocervical
L. internal carotid
à Circle of WillisL. COMMON CAROTID superior epigastric
L. external carotid
à facial/neck arteries
Humoral circumflex a's.
Ulnar
L. SUBCLAVIAN
à Axillary à Brachial Palmar arches à digital a's.Radial
L. vertebral Basiliar
à Circle of WillisL. thyrocervical
à suprascapular à humoral circumflex a's.L. internal thoracic
à ant. intercostal a's.L. costocervical
THORACIC AORTA
(all aortic branches paired, unless otherwise noted)Post. intercostals
Bronchials
Esophageals
Superior phrenics
ABDOMINAL AORTA
Inferior phrenics Hepatic
Celiac (single, anterior branch)
à Left gastricSplenic
Lumbars
Superior mesenteric (single, anterior branch) inferior
Suprarenals epigastric
Renals
Testiculars or ovarians
Inferior mesenteric (single, anterior branch)
middle sacral
Int. iliac
à pelvic region Peronealmed. plantar
COMMON ILIAC (R & L)
à Ext. iliac à Femoral à Popliteal à Post. tibial plantar arches à digital a's lat. Plantarfemoral circumflex Anterior tibial dorsal archs
à digital a'sdorsalis pedis
Major Veins Emptying into SVC and IVC
acc. cephalic
median cubital
Cephalic Basilic
Ulnar
Subclavian
ß Axillary ß Brachial palmar arches ß digital v'sRadial
lateral thoracic
Thoracoepigastric
Internal thoracic
Ext. jugular
ß face/neck v'sVertebral superior sagittal sinus
Int. jugular
ß transverse sinus ß inferior sagittal sinusBRACHIOCEPHALIC
Accessory hemiazygos
Azygos
Hemiazygos
SUPERIOR VENA CAVA
HEART
INFERIOR VENA CAVA
Inferior phrenics
Ascending lumbars
ß lumbarsInf. mesenteric
Hepatics
ß Liver ß Hepatic portal ß SplenicSup. mesenteric
Right suprarenal
Renals
Left suprarenal superficial epigastric
Left testicular or ovarian
Right testicular or ovarian
Middle sacral
Int. iliac Great Saphenous Peroneal
Common iliacs (R & L)
ß .Ext. iliac ß Femoral ß Popliteal ß Post tibial ß plantar arch ß digital v's
Ant tibial
Small saphenous
ß dorsalis pedis ß dorsal arch
How to (possibly) SAVE an Amputated Limb
1. RETRIEVE IT:
Find and retrieve the limb (or all the pieces)- regardless of the condition!
2. RINSE IT:
Rinse off debris (distilled water is better, but tap water is okay).
3. WRAP IT:
Wrap in moistened (clean, if possible) towel(s) or cloth(s).
4. BAG IT:
Place the wrapped part(s) in a plastic bag and seal it.
5. COOL IT:
Place the bagged part(s) on top of ice or cold packs in a cooler (or other container). Keep the part(s) away from direct contact with any water.
[ref: Prairie Farmer, p.54, May, 1988]
Zoo 2200 LYMPHATIC SYSTEM
I. General features of the lymphatic system (Fig. 23-1)
A. Lymph is ultimately derived from blood plasma.
1. Plasma leaves blood capillaries in greater quantities (about 24L/day) than it returns.
A) edema
2. Tissue fluid is the name given to the liquid bathing body tissues.
3. When the tissue fluid collects into a lymphatic capillary, it's called lymph.
4. Lymph drains into the venous system. Thus, it eventually returns to the blood plasma.
B. Lymphatic vessels
1. Lymphatic capillaries are similar to blood capillaries by having thin walls. They differ by being "blind ended" (do not connect two larger vessels). (Fig. 23-2)
A) lacteals
2. Larger lymphatic vessels have structural characteristics similar to veins.
A) valves
3. Right lymphatic duct (Fig. 23-4)
A) Drains lymph from right- half of head, upper limb, and thoracic cavity.
B) Empties into the right subclavian vein.
4. Thoracic duct (Fig. 23-4)
A) Drains left- half of head, upper limb, thoracic cavity, and everything below diaphragm. B) Empties into the left subclavian vein.
II. Main function of the lymphatic system: To provide acquired immunity.
A. humeral immunity- circulating antibodies are produced (globulin proteins) which attack the foreign agent. (Fig. 23-6)
1. During early life, the liver and bone marrow produce "B cells", which migrate to lymph nodes and remain there during adult life. They are the source of circulating antibodies.
2. B cells are the source of the circulating sensitized lymphocytes. About 10-15% of circulating lymphocytes.
B. cellular immunity- specialized lymphocytes are "sensitized" to attach to the foreign agent and invade it.
1. During early life (prepuberty), the thymus gland produces "T cells", which migrate to lymph nodes and remain there during adult life. About 80% of circulating lymphocytes.
NK cells- 5-10%. attack foreign and cancer cells.
III. Acquired Immune Deficiency Syndrome (AIDS) (p.587, 769)
Zoo 2200 LYMPHOID ORGANS
I. Organs
A. Diffuse lymphoid tissue(s) (Fig. 23-8)
B. lymph nodes
C. thymus
D. spleen
E. tonsils
F. All participate, in some fashion, in Ab/Ag activity.
II. Lymph Nodes (Fig. 23-9)
A. Situated along/within lymphatic vessels.
1. The only organ(s) to receive AFFERENT lymphatic vessels.
B. Filter lymph.
C. Site for germinating lymphocytes.
D. Especially numerous in cervical, axillary, and inguinal regions.
E. Structure
1. afferent and efferent lymph vessels.
2. external capsule with trabeculae.
3. cortex with germinal centers
4. medullary cords
5. sinuses
F. lymphoid tissue of mesodermal/mesenchymal origin.
III. Structure and function of Thymus gland (Fig. 23-16)
A. 2 lobes in anterior mediastinum, behind upper sternum.
B. capsule with trabeculae.
C. cortical cells, macrophages, epithelial cells.
D. thymic corpusles (of Hassall).
1. concentric rings of epithelial cells.
2. function unknown.
E. Functions
A) paracortex in lymph nodes.
B) Peyers Patches.
C) paraarterial zones in spleen.
2. controls rate of lymphocyte production.
3. site of massive destruction of lymphocytes.
A) significance unknown.
IV. Structure and function of the Spleen (Fig. 23-17)
A. largest of lymphoid organs.
B. Structure
1. capsule with trabeculae.
2. hilum/hilus
A) All blood vessels.
3. arteries and arterioles with surrounding white pulp.
4. veins and venous sinuses with surrounding red pulp.
C. Functions
1. filters the blood.
A) destroys old erythrocytes in red pulp.
B) stores iron released from breakdown of hemoglobin.
2. produces B-cells
3. phagocytosis (see p. 434)
IV. Tonsils (Fig. 23-8)
A. 3 sets of lymphoid tissue ringing the pharynx- the openning into interior of the body.
1. Palatine
2. Pharyngeal
3. Lingual
B. All have structure similar to lymphoid nodule(s).
C. palatine
1. between glossopalatine & pharyngeopalatine arches.
D. pharyngeal
1. middle of posterior wall of nasopharynx (behind/posterior to nasal cavity).
E. ling