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Useful Things
quick reference
Acronym Database Indiana's famous database of every acronym related to chemistry that you could ever imagine!
Azeotrope Database
  provides data on most known azeotropes; just provide the components
Calculator Java Applet full function calculator
Cooling Baths any temp. you want, using about 50 combinations of salts/ice, solvent/dry ice, and solvent/liquid N2 - very handy!

Digital Nomograph accurately calculates new b.p. at any pressure - choice of units - excellent!
Drying Agents every drying agent in common use, along with its water capacity
Freezing Mixtures various salt-ice (water and dry) giving most temperatures ranges desired
Heating Baths mostly consists of melts of various types, including metal mixtures
Incompatible chemicals compounds that shouldn't contact each other

Javascript Graphing Calculator fill in data, and it shows you how eight common graphs look - great!
Kinetic Resolution   quickly calculates the e.e. possible using KR for compounds with different S values
MegaConverter 2 - convert any unit to any other - very good

Optical Rotation Calculator enter the usual variables, and it provides the rotation.
Osiris Property Explorer  
draw a molecule and it calculates various drug variables: cLogP, solubility, druglikeness, drug-score, & toxicity risks!
Other Java applets four related to light emission/absorption, and four related to thermochemistry
pH Indicators very colorful table

Rotovap Simulator  wondering if you can strip acetone from a compound whose b.p. is 180 °C?  Here's the answer; can accommodate two solutes
Solvent Miscibility Table what solvents are soluble in what
Synthesis Calculator 1.1 automagically calculates mmol, molar eq., etc. - very nice!
TOPNMR Online Demo   draw a molecule, and it predicts both its 1H and 13C NMR absorption values - really nice

news sites
Canadian Society for Chemistry   the "Canadian ACS"
Chemistry.org  the official ACS home site - if you haven't seen it yet, now's the time.
ChemWeb   super news source, features databases, tools, books, breaking chemistry news, etc. (registration is free)
Chemical Institute of Canada   includes chem. engineers, technologists, etc.

databases/reference

Acid Dissociation Constants what you'd expect
Base Dissociation Constants
what you'd expect
Chemical Dictionary
great graphics as well as definitions
Concentrations mass and weight

Data for General, Inorganic, Organic, and Physical Chemistry 36 tables of data, w/thermochem., lattice E, DH, conversions, etc.

IUPAC Compendium of Chemical Terminology the name says it all - from the ultimate source
NMR Chemical Shifts, Carbon excellent compilation
NMR Chemical Shifts, Proton
excellent compilation
NMR Solvent Peaks both 1H and 13C data

On-Line Databases and Software the Chemical Society's (UK) collection of >3000 links
Phosphine Ligands all you'd ever need to know (of course, it's short ;-)
Physical Constants every physical constant you've ever encountered, and many that you haven't

Physical Constants of Solvents including bp/mp, refractive index, dipole moment, dielectric constant, molar refraction

Solvents for Chromatography features the physical constants from above, along with several specific to chromatography
Synthetic Pages - Practical Methods for Synthetic Chemists - loads of submitted procedures - like a non-reviewed Org. Synth.

UIUC Chemistry Library Electronic Journals  the entire holdings of UIUC chem. journals, with the years they have.  Look to see if the ref. you need is there, then just give me the citation; I can have it for you in minutes!
Units, Basic pKb constants
Units, Derived 
many constants derived from the pKb values

comprehensive sites

Laboratory Techniques extraordinarily useful
Organic Chemist's Companion Craig Merlic - UCLA - great
Didactics of Chemistry (University of Regensburg) - demos, experiments (mostly computer-integrated w/CASSY), data analysis, etc.

pKa Tables (most acidities determined in DMSO [by F.G. Bordwell at Northwestern]; many of the others in H2O):
H. Reich (Wisconsin)
D. Evans (Harvard)
Hoveyda (Boston College)

Periodic Tables

translators (on-line) the ones that are chemistry-specific are indented and marked with a blinking lightbulb    Esp. good for you slackers who went to a grad. school that no longer requires proficiency in a foreign language .  It's a mistake, esp. if you're an organiker and don't know German.
AltaVista - BabelFish Translations   can do a cut/pasted paragraph, or an entire web page (enter its URL)
Chemical Terms Translator   common chemical terms rendered into French, German, Russian, and Japanese
IM_Translator   very similar to BabelFish, maybe a few more languages
Langenberg  A COMPOSITE! Seven windows for pasted-in jobs, five for URLs, four for words, even two to guess the foreign language!
WorldLingo  similar in operation to the above, but has lots more languages

German-English Dictionary   by TU Chemnitz, has quite complete database of chemical terms and acronyms
Beilstein German-English Dictionary   from Stanford University, specific for chemistry and chemical engineering
New English-German Dictionary   one of the best!  Can be downloaded onto your own PC
QuickDic  (I'm serious!)   this may be the best of them all


Search Engines and Sources of Chemical Information *requires 14-digit library ID no.
Analytical Chemistry Springboard from Umea University, an extremely diverse link collection dealing with analyt. chem.
ChemACX
  locates chemical suppliers, allows side-by-side comparison of different catalog listings - really useful
ChemConnect  broker connecting sellers & buyers; these folks typically deal in very large quantities.
ChemExper  internat'l. chemical locater; database, including >100,000 chemicals, can be searched by substructure, formula, CAS #, name, etc.
ChemFinder   provides physical data, sources, health info, OSHA regs, and much more

Chemical and Physical Properties   great utility for finding reference books for any physical/chemical properties you could imagine

Chemical Databases Chemistry   very nice collection of link libraries for all areas of chemistry
ChemIDplus Chemical Search Input Page National Library of Medicine

Chemistry Internet Resources: LSU Webliography  link to web sites for chemical data, esp. fullerenes, pesticides, and phys. properties
Chemistry Journals On-Line at Booth Library* includes every issue, back to vol. 1 #1, for every ACS journal; also many non-ACS journals

European Patent Office, The  network of patent databases, covering 30M documents
Jinno Laboratory Research Information research information on LC, SFC, PAHs, and Drug/Pesticide databases

Library of Chemistry Information - FDA links for databases, food chemistry, journals/conferences, software, lab equip., etc.
Manage PowerPoint Presentations from Univ. of Manchester, very good outline
National Library of Medicine Gateway enables simultaneous searching of eight large databases in the biomedical field

NetSci  an on-line publication which features scientific focus articles and resources in pharmaceutical/biotech areas
NIST Chemistry WebBook    Database of thermochemical, thermophysical, and ion energetics data compiled by NIST
Ovid* gateway to many search engines, using ILLINET as primary database
Paperchase  search five medical databases at once: MedLine, HealthStar, AidsLine, CancerLit, OldMedLine

Patents - U.S. Patent and Trademark Office    can search for both issued and applied for patents, incl. full-text
PubMed   MedLine, the best medical literature database around - FAST

Sci-Info Information Resource Guide    long list of chemistry books, with call no.'s, a few of which are on-line
Scirus  science-specific search engine, replacing BioMedNet.com; searches 120M web pages from free and journal sources - excellent

SINTEF a Norwegian consulting/research firm, with expertise in many chemical areas, from catalysis to synthetic organic chemistry
STUN on the Web need the Dept. login/PW; use academic login
Tetrahedron.info  very useful; primarily from the Tetrahedron trio of journals
Trinity University Chemiinformatics Site much web info, software, "Best of the Chem Web", chemgrad programs, etc.
Univ. of Illinois-Chicago "Electronic Reference Shelf" has links to Med line, Merck Manual, MayoClinic, Gray's Anatomy, etc.

WebReactions a reaction search retrieval system - takes just a little learning, but then it's powerful

WWW Chemicals on CHEM.COM  search catalogs (and find co.s' homepages) by name or substructure, find equipment, find custom synthesis, etc.
.

Chemistry Publishers  [for links to specific journals, see Chemistry Journals]

ACS Publications American Chemical Society
Chemical Society of Japan (CSJ) - just what it says!

Chemistry Journals  since 1995, one of the world's most comprehensive, link-checked lists of internet-linked chemistry-related journals.
Delphion Intellectual Property Network - US Patents
Elsevier Science journals - Organic Chemistry (the "Tetrahedron trio")
Europe's Network of Patent Databases - EP & WO 
Kluwer Online - Kluwer Online Gateway

RSC Journals - Royal Society of Chemistry
ScienceDirect - WebEdition Journals
Thieme Chemistry - Thieme  (Synthesis, Synlett)

Wiley-InterScience - Chemistry Journals
UdeM's list of Online Journals


Comprehensive Sites - Collections of Useful Links in All Areas
2000 of the Best Chemistry Sites from Cambridge University - chem. dept's journals, societies, databases - incredible
Basic Concepts of Chemistry (from Wiley) supplemental on-line exercises and links to tutorials - HUGE!

Beer's Law
very nice review
ChemDex  "the directory of chemistry on the WWW since 1993" - if they say so themselves!
Chemie.DE  the German equivalent of ChemWeb - a great clearinghouse, with links, a slick "toolbox", news briefs, etc.
Chemistry (from the Mining Co.) original/archived articles, topics include organic, environmental, and medicinal chemistry.
Chemistry Library at UIUC; Internet Resources for Chemistry
self-explanatory; great resource
Chemistry Resources on the Web  refreshingly selective link collection - safety, societies, jobs, on-line tools, literature, etc.
Chemistry Webercises Directory  huge, well-indexed, complete links compilation; ends w/list of many more links collections
ChemWeb  there's so much here, it can't be summarized - huge, multifaceted chemistry site; access to journals, databases, etc.

Division of Chemistry - On-Line Learning
resources for physical and analytical chemistry
CrossRef  "The Central Source for Reference Linking" - click on a citation and you're taken right to the target content
Glassware Gallery
along with pointers on how to prepare broken glassware so as not to annoy your local glassblower, there are several pointers about glassblowing:
dot Glassware Joints
dot Fritted Funnels
dot Gas Regulators
dot Heating Sources
dot Bubblers

dot Global Instructional Chemistry
  diverse, but not too developed yet - 50 links total
HighWire -- Free Online Full-text Articles   Stanford Univ.; nicely conceived
Hungarian Academy of Sciences' Chemical Research Center concise, not-too-voluminous link collection

Martindale's Reference Desk: Chemistry Center  huge, complete link collection from UC-Irvine
Quantum Chemistry 
a very nice outline of the basics behind quantum mechanics as applied to chemical problems
Rolf Claessen's Chemistry Index   one of the truly excellent link compilations - superb indexing
SHMO - The Simple Huckel M.O. Theory Calculator a neat embodiment of high-level computers that calculates MO energy levels
Sources for the Synthesis or Reactions of Compounds Indiana University's excellent resource collection
Virtual ChemBook  large collection of chapters covering everything from standard org. chem. to drug action to biochemical cycles
Virtual Chemistry from Oxford Univ.  several interactive lab exercises, along with other virtual learning sites. From Oxford Univ.
Virtual Library for Chemists the incredible Liverpool site, with over 8400 links
U.S. National Library of Medicine  tons of resources: health info, databases, catalogs, research programs, shifting exhibits...
WWW Chemistry Resources (UCLA)   good starting point for WWW searches

BUBL LINK/5:15 (click image for BUBL homepage):
BUBL homepage
Gen'l Purpose Chem
Organic Chemistry
Chemical Engineering
Chemistry Research
Chemical Education
Chemistry Links

Organic Chemistry
Molecules of the Month
Electronic Conferences on Trends in Organic Chemistry
Organic Chemistry
Organometallic Chemistry
1995
1997
Beginners' Guide to Organic Synthesis very basic intro to the concepts of conceiving an organic synthesis
Centre for Molecular and Biomolecular Informatics 
free molecular and reaction modelling
ChemVis  chemical visualization on the internet

CIRRUS
  an undergraduate chemical research resource

Gordon Research Conferences Home Page
 
the best conferences around - Prof. Hans Reich, Univ. of Wisconsin-Madison

Molecular Diversity, Combinatorial Chemistry, and Solid Phase Synthesis from CSPS Pharmaceuticals
Name Reaction List   very nice, color coordinated, from MonomerChem
Named Reactions    Prof. Hans Reich, Univ. of Wisconsin-Madison
Named Reagents
  
Prof. Hans Reich, Univ. of Wisconsin-Madison

Named Rules and Effects   very handy - Prof. Hans Reich, Univ. of Wisconsin-Madison
Organic Chemistry - Directory of Online Resources   list of useful links
Organic Chemistry Forum  the organic part of ChemWeb (section 2, above) - fantastic site
Organic Chemistry Info undiscovered treasure! - Prof. Hans Reich, Univ. of Wisconsin-Madison

Organic Chemistry Resources Worldwide an intuitive WWW resource guide for synthetic organic chemists - maybe the best
Organic Chemistry Text On Line  Prof. William Reusch - magnificent!
Organic Division Info  from the ACS division - covers rxns., nomenclature, cmpds., & NMR.
Organic Synthesis Exploration Tool (OSET)    aplet-based synthetic disconnection tool - very good, esp. for a  Windows-based program
Organometallic HyperTextBook Index, The a really great resource - readable and rigorous

Other Organic Chemistry Resources a gathering of resources from other sites, most of which are included in this compilation
Pericyclic and other Orbital Symmetry-Controlled Reactions
- orbital symmetry, Woodward-Hoffman Rules, electrocyclic/sigmatropic rxns,
Phosphine Ligands a short listing of typical phosphine ligands used in asymmetric catalysis
Reactive Intermediates 
listing by Prof. Hans Reich of the common types of reactive intermediates
Synthesis Reviews Database
 
a database of over 15,000 review articles of interest to synthetic organic chemists.
St Hugh's College Organic Chemistry Web visually superb, a great comprehensive site - Requires IE!
Tetrahedron.info  free access to TOC and abstracts for all five Elsevier journal
TORVS chemical internet services an incredible number of free computational services, from calc. & visualization of orbitals to modeling applications
Web-Sters Organic Chemistry a "Living Document of Internet Resources", Information and Applications
Chemical/Lab Equipment Suppliers*
Mallinckrodt Strem Chemicals Alfa Aesar Chemcyclopedia
Exclusive Chemistry Ltd
* This is not an exhaustive list; for more chemical dealers, try using Google on "laboratory" or "research chemicals", etc.

Organic Chemistry Course Materials
Advanced Organic - Harvard (Chem206):
Fa2000
Fa2001
Fa2002



Advanced Organic Chemistry: Synthesis of Complex Molecules
: Harvard (Chem115 - Andy Myers)
PSIgate Chemistry Gateway  links to hundreds of 31 handouts, databases, course homepages, lecture notes, tutorials, etc. - very complete
Organic and Inorganic Chemistry - Imperial College - includes the following:
Virtual Chemistry - Virtual Laboratory - Oxford super site - worth a look around!
O=CHem Directory -from Univ. of S. Maine - with tutorials on every topic, with interactive exercises and quizzes - great!

Spectroscopy/Chromatography
Analytical Chemistry Springboard, The   Umea Univ. (Sweden) collection of analytical links, to both techniques and data resources
Beer's Law - Theoretical Principles    from Sheffield-Hallam Univ. (UK) - nice tutorial

Chemical Concepts   "sophisticated spectroscopic software" coordinating >660,000 spectra (world's largest!)

Chromatography - Introductory theory
    from Sheffield-Hallam Univ. (UK) - nice tutorial

CLOGP Predictor
calculation of hydrophobicity as Log P (o/w)
EuroSpec - International Spectroscopic Data Bank not really off the ground yet, but their graphics are great!
Gas Chromatography   
from Sheffield-Hallam Univ. (UK) - nice tutorial

Integrated Spectral Data Base System (SDBS)
the great Japanese site to which others only aspire - typical spectra with a HUGE database
Molecular Monte Carlo Home Page  a great site if you're interested in Monte Carlo methods, from classical to quantum mechanical

Molecules Help Page also from Purdue, everything you wanted to know about moleclues
Online Guide to Chiral HPLC - very good primer from Mark Earll's web page; Earll is an analytcial chemist.
Organic Structure Elucidation   "A Workbook of Unknowns"
SpectroscopyNOW
  The New Online Resource Serving the Spectroscopy Community
OSIRIS Property Explorer predicts molecular properties, incl.cLogP, toxicity, sol'y., MW, drug likeness (fragment-based and overall)
Solutions Help Page from Pursue, everything you wanted to know about solutions, along with a nice chemistry glossary
Spectra OnLine  not quite as large as the Japanese site, but fast and still very large database
Spectroscopy Home   from UIC, very good synopses of the major types of spectroscopy, along with self-tests and problems.  Great review.
Spectroscopy Resources Chemical Institute of Canada -very diverse, w/hypertexts, journals, databases, abstracts, software, research groups, societies
Spectroscopy Tools Online 
Univ. of Pottsdam, incl. pgs. w/shift tables (H,B,C,N,O,F,P), J values, periodic table, NMR solvents, etc.
TOPNMR
 
On-Line Demo on-line prediction of 1H and 13C NMR shift data
UV-Vis Absorption Spectroscopy - Theory  from Sheffield-Hallam Univ. (UK) - nice tutorial

Infrared Spectroscopy

NMR Spectroscopy
Visual Quantum Mechanics  great site to explore if you don't get the concepts of quantum mechanics
Pharmacology/Medicinal Chemistry/Biochemistry/Cell Biology

Cell Biology Animation  you name it, he's got a Flash animation - also covers architectural art, graphics, "3D", stochastic, etc.
Bio materials Network  resource center for anyone working with biological materials - links, conferences, leading references, etc., etc.
Drugs.Com  a very complete, huge database on Rx and OTC drugs of all kinds

Elsevier’s Drug Discovery Gateway on BioMedNet
  just what it says - excellent resource!

First Course in Pharmacokinetics and Biopharmaceutics
  complete, well-referenced and illustrated on-line course
Fundamentals of Drug Action - Stereochemistry  nice collection of graphics/data on the effects of chirality of biological action

Intermolecular Forces
  a very good review; yes, you do need to review this!!
Introduction to Drug Action  from the virtual ChemBook - a very good introduction to the concepts of xenobiotics and how the body deals with them
Medical Pharmacology  great, on-line book - check it out; you'll be amazed at its depth and excellent graphics
Medicinal and Poisonous Plant Databases  databases covering poisonous plants, medicinal plants, and mistletoe (!)
Merck Manual, The  the time-honored text of diseases, their etiology, course, Tx, etc.

Metabolism Overview
  includes cell structure, ATP, glycolysis, electron transport, energy transfer in cells, the important biochemical cycles, etc.
On-Line Biology Book  (yes; that's its real name) a complete, 59 chapter, well illustrated book on basic biology
Pharmacokinetics   a very cool collection of graphics and javascript programs illustrating drug distribution, absorption, excretion, metabolism, etc. 
Pharmacokinetics/Pharmacodynamics  course home page from Univ. of OK College of Pharmacy
Pharmacy Databases on the WWW
  lots of links on all aspects of pharmacy, pharmacology, medicinal chemistry, etc.
Principles of Drug Action  fnc. grps., acid-base chemistry, amd physicochemical propeties

RxList
  easily the best all-around site for drug information, incl. indications, uses, clinical pharm., overdoses, side-effects, etc.

Virtual Autopsy, The  just what it sounds like - try it; you'll like it!

Safety and Ethics
10th Report on Carcinogens NIH's periodical review of the state of carcinogenesis
ATSDR's HazDat Database   front end to the hazardous substance release and health effects database
CCINFOweb   Canadian safety site; databases include CHEMINFO (safety data), OSH (worldwide safety lit.), legislation, etc.
Chemist's Code of Conduct from ACS, a description of chemists' responsibilities towards all parties

Emergency Response Guidebook
from Transport Canada, a complete response handbook - great job
Ethical Guidelines to Publication of Chemical Research - ACS (pdf) self-explanatory
Ethics OnLine  "The OnLine Ethics Center for Engineering and Science" - super, large, complete site with many links

Hazardous Chemical Database
Univ. of Akron site; each "hit" provides large, four-screen safety profile

IPCS INCHEM   chemical safety data - includes great "chem. safety cards", health/safety guides, antidote data, much more

MDL Information Systems - Downloads
 
includes the Drug Data Report, Toxicity Finder, and other health/safety-related items
Oxford Univ.'s Safety Site amazing site, incl. buffers,carcinogens, MSDS, peroxides, flash points, gloves, gases, much more

Poisons Information Monographs V   from IPCS, covers hundreds of chemicals
Prudent Practices in the Laboratory Table of Contents - 1995
RTECS Database Search Engine CCINFOweb's RTECS search engine

Where to Find Material Safety Data Sheets
Looking for a Graduate School? A Job? A Chemical Conference?
Synthetic Chemistry
Academic Chemistry Departments in the United States
complete listing

Academic Chemistry Departments Outside the US just what it says
Adviser, Teacher, Role Model, Friend a great open book on mentoring students in science and engineering

Chemical Society's Conferences/Events Homepage
search by discipline, avail. time, organizer, etc
.
Chemistry Conferences    the source for them all - conferences, exhibitions, and trade fairs

Organic Synthetic Groups in Canada 
   quite complete, maintained by the same chemist who does the US list

Organometallic Research Groups
    covers N. America
Pharmaceutical Companies a listing of the top several dozen pharmas, along with their primary web sites
Synthetic Research Groups - USA virtually every synthetic organic group in the country. Continually updated.
What to do with a Major in Chemistry in case you forget why you're putting yourself through all this!

Medicinal Chemistry

Academic and Government Medicinal Chemistry Sites
  
lists the best programs in the country, both in academia and government

ACS Division of Medicinal Chemistry 
under "Links", lists the 20-30 strongest graduate programs
Anita's Web Picks  
a somewhat eclectic, but comprehensive selection of graduate programs, databases, computational sites, etc. in medicinal chem.

Grad. Schools.com
 
a nicely organized site; you can click on the state(s) you're interested in; other listings are also linked
Medicinal Chemistry in IUPAC
Accomplishments During the Past Decade and Relationships With Industry.

Medicinal Chemistry in the New Millennium
from Chemistry International
Other Cool Sites   from VCU, a large listing of medicinal links, including academic programs, industrial sites, online courses, computatioinal links, etc.

Want to be a Better Writer/Speaker?
ACS Style Guide A Manual for Authors and Editors
ACS Handbook for Speakers everything you could ever want to know, and then some

APA Style Guide
  the format used by ACS
Citing Your Sources - Citation Style Guides  great resource from Wright State Univ.
Effective Presentations from KU Medical Center, a very complete and comprehensive on giving a dynamite talk
Guidelines for Hosting an ACS Meeting from ACS
Language Help Pages guidelines for scientific presentations
Oral Skills a very good outline on honing the orla skills all scientists must have
Poster Preparation Guidelines from Univ. of Chicago
Style Manuals  a selection of various style guides

Tips for Giving Scientific Presentations a short, but very useful link list for web resources on giving the best talk you possibly can
Tips for Preparing Scientific Presentations from a scientist in the limitary, very well thought out

Welcome to (EIU's) Writing Center!
  lots of links ot useful resources about grammar, sentence construction, etc.
"How To" Series from Kansas Med. School Journal Abbreviations Acronyms
Fun/Interesting Stuff!
"The Elements" song (Lehrer), animated! if you've never heard this before (or even if you have), you must see the animation!!

QuackWatch
  from a now-retired psychiatrist who grew sick of quacks, questionable product claims, etc.  Check it out!!!
Glassblowing Tips   from E. Caroline Univ., a nice collection of data about scientific glassblowing, glass recipies, tools, torches/burners, etc.
Glasstopia  cool site; the link is to award-winning entries (non-scientific), some of which are breathtaking!
Scientific Glassblowing Basics  from the ECU page; this covers pretty much every task you'd need, from cutting/bending glass to ring and vacuum seals

Science Jokes
  from The Netherlands - some great, some awfull
Innocentive  Feeling creative? A series of compounds for which synthetic sequences are being solicited - they pay between $5K and $75
AFU & Urban Legends Archive
  awesome collection

Chemistry of How Things Work, The really fascinating collection of case studies from carcer chemotherapy to Gatorade to fuel cells

"Chem 211 Songs" from "Grignard the Beautiful" to "Glory, Glory It's Wolff-Kischer", a collection of cute tune commemorating important chem. events

Nanotube Site, The
  just super
The T.W.I.N.K.I.E.S. Project the results of testing the venerable food item in every way imaginable, esp. its legendary longevity

The Onion|America's Finest News Source
if you haven't checked The Onion, you don't have the whole story!

Alex Chiu's Eternal Life Device
even after you see this, you won't be sure if this guy's for real

Daryl Cagle's Professional Cartoonists Index!
the best political cartoon site anywhere - super subject index!

OXYmoron Humour Archive: Scientific Articles
what every scientist must read to stay informed of the latest important developments
University of Slough - Department of Perpetual Motion and you thought this was impossible!!    
Molecules with Silly or Unusual Names
  great comic relief!

Straight Dope, The
  Cecil Adams answers those questions nagging mankind but whose answers have proven so elusive...

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